IRVAN Syndrome

Abstract

Objective: To report a case of idiopathic retinal vasculitis and neuroretinitis (IRVAN) syndrome.

Methods: This is a case report.

Results: A 35-year-old Caucasian male was referred for evaluation of posterior uveitis. Vitritis, retinal vasculitis, and capillary dropout in the peripheral retina were observed. Fluorescein angiography confirmed the changes. Systemic and blood work-up revealed negative findings. Oral steroid combined with a systemic immunosuppresant had no effect on the disease course. The pattern of the disease and lack of response to immunosuppresives were consistent with a diagnosis of IRVAN syndrome. The patient remained on regular follow-up and maintained good visual acuity of 6/6 in the affected eye.

Conclusion: Clinicians should be aware of the existence of IRVAN syndrome to prevent injudicious use of steroids and systemic immuno-suppresants in these patients.