Vol. 48 No. 2 Surgical Technique PDF

Cytopuncture Microbiopsy during Transcanalicular Endoscopic Lacrimal Duct Recanalization: A Novel Approach

Reynaldo M. Javate MD FICS1 , Rolando A. Lopez MD2

1University of Santo Tomas Hospital Eye Institute and Department of Ophthalmology, University of Santo Tomas Hospital, Manila
2Section Chief of Cytophatology, Department of Anatomic Pathology, University of Santo Tomas Hospital, Manila

Correspondence: Reynaldo M. Javate, MD, FICS
Clinic Address: Rm. 501, Doctors’ Clinics, 5th Floor, Clinical Division, University of Santo Tomas Hospital, España Blvd, Sampaloc Manila, Philippines 1008
Clinic Phone Number: +632-296-3636/ +632-731-3001 local 2516
E-mail: rmjavatemd@gmail.com

Disclosure: The authors report no financial conflict of interest.


Objective: To describe the cytopuncture microbiopsy (CM) technique performed during transcanalicular endoscopic lacrimal duct recanalization (TELDR) in patients with primary acquired nasolacrimal duct obstruction (PANDO) as an alternative to open biopsy, the standard method used in collecting specimen.

Methods. This is a noncomparative, interventional case series with histopathologic correlation. Patients diagnosed with complete PANDO who underwent TELDR with balloon dacryoplasty and silicone intubation with CM at University of Santo Tomas Hospital from October 2014 to January 2017 were included.

Results: Twenty (20) tissue specimens from the lacrimal sac and nasolacrimal duct were obtained from 18 patients. There were 16 females and 2 males included in the study. Mean age was 57.5 years. All specimens revealed few clusters of benign epithelial cells with few degenerated mononuclear cells and lymphocytes, and singly scattered lymphocytes that are set in fibrinous background. Tissue cytology studies were negative for malignant cells.

Conclusion: CM is a minimally invasive procedure that offers an alternative to open biopsy technique that can be done routinely during TELDR.

Keywords: Cytopuncture microbiopsy, Transcanalicular endoscopic lacrimal duct recanalization, Primary acquired nasolacrimal duct obstruction, Dacryocystorhinostomy, Epiphora