A case of intracranial chordoma associated with multiple-cranial-nerve palsy
Ali A. Bodla, MD, Syed A. Ali, MRCS, Bruce Hutchison, FRCS Ed, FRCOphth
Objective
To report a case of intracranial chordoma associated with multiple-cranial-nerve palsies, highlight its presenting features, and evaluate treatment options for this rare neoplasm.
Methods
This is a case report.
Results
A 77-year-old man presented with diplopia and left sixth-nerve palsy. Further investigations revealed an intracranial chordoma. Surgical decompression was performed which resulted in complete resolution of the diplopia. Three months postsurgery, he was noted to have a right-third-nerve palsy. Repeat MRI showed tumor recurrence. Targeted proton-beam-charged-particle therapy was performed.
Conclusion
Radiation therapy using targeted proton-beam-charged particle was shown effective in the treatment of intracranial chordoma, resulting in significant improvement in ocular motility and resolution of ptosis.