Frosted-branch angiitis with central-retinal-vein occlusion: angiographic and OCT findings

Abstract

Objective: To report angiographic and optical-coherence-tomography findings in a case of frosted-branch angiitis (FBA) with central-retinal-vein occlusion (CRVO).

Methods: This is a case report.

Results: A healthy Japanese female presented with monocular blurring of vision. Fluorescein angiography (FA) revealed extensive dye leakage from the retinal blood vessels and optic-nerve head. Indocyanine-green (ICG) angiography demonstrated tortuous retinal veins containing foci of hypo-fluorescence, foci of hyper-fluorescence, and diffuse dye leakage. Late choroidal hypo-fluorescent patches were observed. Optical coherence tomography demonstrated swelling of the optic-nerve head and thickening of the sensory retina and nerve-fiber layer. Aggressive steroid treatment resulted in improved vision and angiographic appearance.

Conclusion: CRVO may be an initial presentation of FBA. FA, ICG, and nerve-fiber-layer OCT examinations are useful in monitoring disease resolution. Early and aggressive steroid treatment can help control inflammation and improve visual outcome.