Criteria for the timing of the initial retinal examination to screen for retinopathy of prematurity

Milagros H. Arroyo, MD, MPH, Dino L. Camonias, MD, Andrea Kristina Monzon-Pajarillo, MD, Farlah Angela M. Salvosa-Sevilla, MD Junn R. Pajarillo, MD, Aldous de Leon, MD, Gabrielle S. Evangelista, MD

To determine the applicability of a modified criteria for initiating retinal examinations to screen for retinopathy of prematurity (ROP).

All ROP charts of babies who had initial retinal examination to screen for ROP from January 1, 2005 to December 31, 2008 at the neonatal-intensivecare nursery and eye center of a tertiary hospital were reviewed. Date of birth, sex, age of gestation (AOG), birth weight (BW), postnatal age (PNA), postconceptional age (PCA), and ROP classification were recorded. Descriptive statistics and Student’s t-test were used to analyze the data.

A total of 690 eyes of 345 babies, 174 males and 171 females, were included in the study. At the initial retinal exam, the mean AOG was 31.39 ± 2.46 weeks; BW, 1,268.77± 317.12 grams; PNA, 4.56 ± 2.95 weeks; and PCA, 35.94 ± 3.26 weeks. Immature retinas in both eyes were seen in 175 (50.72%) babies, while 113 (32.75%) had ROP of any stage in both eyes and 51 (14.78%) had immature retina in one eye and ROP of any stage in the other eye. Among the 113 babies with ROP, 33 (29.2%) were assessed to have pre-threshold ROP.

This study supported the applicability of the modified criteria which are in agreement with the Joint Statements of the American Academy of Pediatrics, American Academy of Ophthalmology and American Association of Pediatric Ophthalmology and Strabismus, and the United Kingdom Royal College of Pediatrics and Child Health for initiating retinal exams to screen for ROP.

Keywords: Retinopathy of prematurity, Screening criteria, Initial retinal exam